The ongoing digital transformation is reshaping industries, economies, and societies worldwide. Advanced 5G technologies are playing a pivotal role in enabling this transformation, offering faster connectivity, reduced latency, and improved reliability compared to previous generations of mobile networks. These technologies enable a wide range of applications, such as the Internet of Things (IoT), smart cities, autonomous vehicles, and advanced manufacturing. However, the rapid development and deployment of advanced 5G technologies have also exposed gaps in the existing workforce’s skills and knowledge. The current education and training systems have not kept pace with the rapid technological advancements, resulting in a shortage of professionals with the necessary digital, green, and entrepreneurial skills. Moreover, there is a need for better collaboration between academia, industry, and research to ensure that the knowledge generated in these domains is effectively transferred and applied. The 5G-DiGITs Alliance project aims to address these challenges by fostering innovation, entrepreneurial mindsets, and knowledge exchange among higher education, vocational education and training (VET), and industry partners. The alliance’s objectives and activities are designed to support the development of a skilled workforce capable of driving the digital and green transitions in Europe, ensuring that the benefits of advanced 5G technologies are broadly shared and contribute to sustainable development.